BBrainOutput

Compatible devices for Qwen2.5 72B

Every hardware profile in our catalog graded for Qwen2.5 72B, best fit first. For sellable vendor configurations, see the device catalog.

Just the best hardware →

  • Supermicro 8x H100 SuperServer
    Supermicro · AI Servers

    Fits at FP16 (~145GB) with ~418.2GB headroom — about 3 concurrent instances.

    FP16 · ~145GBRuns well
  • Dell PowerEdge XE9680
    Dell · AI Servers

    Fits at FP16 (~145GB) with ~418.2GB headroom — about 3 concurrent instances.

    FP16 · ~145GBRuns well
  • AMD Instinct MI300X
    AMD · Datacenter GPUs

    Fits at FP16 (~145GB) with ~24GB headroom — about 1 concurrent instance.

    FP16 · ~145GBRuns well
  • NVIDIA H200 (141GB)
    NVIDIA · Datacenter GPUs

    Fits at Q8_0 (~78GB) with ~46.1GB headroom — about 1 concurrent instance.

    Q8_0 · ~78GBRuns well
  • Cloud H200 141GB (profile)
    Cloud · Cloud GPU Profiles

    Fits at Q8_0 (~78GB) with ~46.1GB headroom — about 1 concurrent instance.

    Q8_0 · ~78GBRuns well
  • NVIDIA H100 (80GB)
    NVIDIA · Datacenter GPUs

    Fits at Q4_K_M (~44GB) with ~26.4GB headroom — about 1 concurrent instance.

    Q4_K_M · ~44GBRuns well
  • Cloud H100 80GB (profile)
    Cloud · Cloud GPU Profiles

    Fits at Q4_K_M (~44GB) with ~26.4GB headroom — about 1 concurrent instance.

    Q4_K_M · ~44GBRuns well
  • HP Z8 Fury G5 Workstation
    HP · AI Workstations

    Fits at Q8_0 (~78GB) with ~6.5GB headroom — about 1 concurrent instance.

    Q8_0 · ~78GBRuns well
  • Lenovo ThinkStation PX Workstation
    Lenovo · AI Workstations

    Fits at Q8_0 (~78GB) with ~6.5GB headroom — about 1 concurrent instance.

    Q8_0 · ~78GBRuns well
  • Supermicro AI Workstation
    Supermicro · AI Workstations

    Fits at Q8_0 (~78GB) with ~6.5GB headroom — about 1 concurrent instance.

    Q8_0 · ~78GBRuns well
  • Quad RTX 4090 AI Workstation (reference profile)
    Reference · AI Workstations

    Fits at Q8_0 (~78GB) with ~6.5GB headroom — about 1 concurrent instance.

    Q8_0 · ~78GBRuns well
  • NVIDIA A100 80GB
    NVIDIA · Datacenter GPUs

    Fits at Q4_K_M (~44GB) with ~26.4GB headroom — about 1 concurrent instance.

    Q4_K_M · ~44GBRuns well
  • Cloud A100 80GB (profile)
    Cloud · Cloud GPU Profiles

    Fits at Q4_K_M (~44GB) with ~26.4GB headroom — about 1 concurrent instance.

    Q4_K_M · ~44GBRuns well
  • Apple Mac Studio (M2 Ultra)
    Apple · Apple Silicon

    Fits at Q8_0 (~78GB) but limited bandwidth makes token generation slow for a 72B model.

    Q8_0 · ~78GBRuns slowly
  • Apple Mac Studio (M4 Max)
    Apple · Apple Silicon

    Fits at Q8_0 (~78GB) but limited bandwidth makes token generation slow for a 72B model.

    Q8_0 · ~78GBRuns slowly
  • NVIDIA DGX Spark (GB10)
    NVIDIA · AI Appliances

    Fits at Q8_0 (~78GB) but limited bandwidth makes token generation slow for a 72B model.

    Q8_0 · ~78GBRuns slowly
  • ASUS Ascent GX10 (GB10)
    ASUS · AI Appliances

    Fits at Q8_0 (~78GB) but limited bandwidth makes token generation slow for a 72B model.

    Q8_0 · ~78GBRuns slowly
  • Dell Pro Max with GB10
    Dell · AI Appliances

    Fits at Q8_0 (~78GB) but limited bandwidth makes token generation slow for a 72B model.

    Q8_0 · ~78GBRuns slowly
  • AMD Ryzen AI Max Mini PC (Strix Halo class)
    AMD · Mini PCs

    Fits at Q8_0 (~78GB) but limited bandwidth makes token generation slow for a 72B model.

    Q8_0 · ~78GBRuns slowly
  • Apple Mac mini (M4 Pro)
    Apple · Apple Silicon

    Fits at Q4_K_M (~44GB) but limited bandwidth makes token generation slow for a 72B model.

    Q4_K_M · ~44GBRuns slowly
  • Dell Precision 7960 AI Workstation
    Dell · AI Workstations

    Even the smallest quantization (~44GB) exceeds usable memory (~42.2GB). Choose a smaller model or step up the hardware.

    Not recommended
  • Coding Agent Workstation (reference profile)
    Reference · AI Workstations

    Even the smallest quantization (~44GB) exceeds usable memory (~42.2GB). Choose a smaller model or step up the hardware.

    Not recommended
  • NVIDIA L40S
    NVIDIA · Datacenter GPUs

    Even the smallest quantization (~44GB) exceeds usable memory (~42.2GB). Choose a smaller model or step up the hardware.

    Not recommended
  • Cloud L40S 48GB (profile)
    Cloud · Cloud GPU Profiles

    Even the smallest quantization (~44GB) exceeds usable memory (~42.2GB). Choose a smaller model or step up the hardware.

    Not recommended
  • Law Firm Private AI Box (reference profile)
    Reference · AI Appliances

    Even the smallest quantization (~44GB) exceeds usable memory (~42.2GB). Choose a smaller model or step up the hardware.

    Not recommended
  • NVIDIA RTX 6000 Ada Generation
    NVIDIA · Professional GPUs

    Even the smallest quantization (~44GB) exceeds usable memory (~42.2GB). Choose a smaller model or step up the hardware.

    Not recommended
  • AMD Radeon PRO W7900
    AMD · Professional GPUs

    Even the smallest quantization (~44GB) exceeds usable memory (~42.2GB). Choose a smaller model or step up the hardware.

    Not recommended
  • NVIDIA RTX A6000
    NVIDIA · Professional GPUs

    Even the smallest quantization (~44GB) exceeds usable memory (~42.2GB). Choose a smaller model or step up the hardware.

    Not recommended
  • Accounting / Odoo AI Box (reference profile)
    Reference · AI Appliances

    Even the smallest quantization (~44GB) exceeds usable memory (~21.1GB). Choose a smaller model or step up the hardware.

    Not recommended
  • Small Business Mini PC (reference profile)
    Reference · Mini PCs

    Even the smallest quantization (~44GB) exceeds usable memory (~22.4GB). Choose a smaller model or step up the hardware.

    Not recommended
  • NVIDIA GeForce RTX 4090
    NVIDIA · Consumer GPUs

    Even the smallest quantization (~44GB) exceeds usable memory (~21.1GB). Choose a smaller model or step up the hardware.

    Not recommended
  • Apple Mac mini (M4)
    Apple · Apple Silicon

    Even the smallest quantization (~44GB) exceeds usable memory (~22.4GB). Choose a smaller model or step up the hardware.

    Not recommended
  • AMD Radeon RX 7900 XTX
    AMD · Consumer GPUs

    Even the smallest quantization (~44GB) exceeds usable memory (~21.1GB). Choose a smaller model or step up the hardware.

    Not recommended
  • NVIDIA GeForce RTX 3090
    NVIDIA · Consumer GPUs

    Even the smallest quantization (~44GB) exceeds usable memory (~21.1GB). Choose a smaller model or step up the hardware.

    Not recommended
  • Dual RTX 3060 Local Server (reference profile)
    Reference · AI Servers

    Even the smallest quantization (~44GB) exceeds usable memory (~21.1GB). Choose a smaller model or step up the hardware.

    Not recommended
  • Local Office AI Appliance (reference profile)
    Reference · AI Appliances

    Even the smallest quantization (~44GB) exceeds usable memory (~14.1GB). Choose a smaller model or step up the hardware.

    Not recommended
  • Hotel AI Automation Box (reference profile)
    Reference · AI Appliances

    Even the smallest quantization (~44GB) exceeds usable memory (~14.1GB). Choose a smaller model or step up the hardware.

    Not recommended
  • Intel Arc A770 16GB
    Intel · Consumer GPUs

    Even the smallest quantization (~44GB) exceeds usable memory (~14.1GB). Choose a smaller model or step up the hardware.

    Not recommended
  • Intel Arc B580 12GB
    Intel · Consumer GPUs

    Even the smallest quantization (~44GB) exceeds usable memory (~10.6GB). Choose a smaller model or step up the hardware.

    Not recommended
  • NVIDIA GeForce RTX 3060 12GB
    NVIDIA · Consumer GPUs

    Even the smallest quantization (~44GB) exceeds usable memory (~10.6GB). Choose a smaller model or step up the hardware.

    Not recommended

Run Qwen2.5 72B privately

Run your own AI agents on hardware you control — private by design, no per-seat data leaving your premises. BrainOutput helps you pick the right machine and turn it into a working AI Business OS.